glutathione deficient rbcs G6PD Deficiency • Glucose-6-phosphate dehydrogenase deficiency • X-linked recessive disorder • Leads to low NADPH, impairing regeneration → are vulnerable to oxidative damage ⸻ Pathophysiology: In G6PD deficiency: • No Glutathione peroxidase - Wikipedia
Glutathione peroxidase Wikipedia Fava beans contain potent oxidant compounds that place a heavy oxidative load on red blood cells. Normally, G6PD generates NADPH to keep glutathione in its reduced, protective form. In G6PD Glutathione production and turnover in RBC. Schematically presented are Download Scientific Diagram Glutathione Cycle As a red blood cell Pathway
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