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G.KogaM.ShafferL

Gynecol Endocrinol

44 , S167S174 (1998)

The best studied mechanism of response to hypoxia involves hypoxia inducible factors (HIFs), which are stabilized by low oxygen availability and control the expression of a multitude of genes, including those involved in cell survival, angiogenesis, glycolysis, and invasion/metastasis