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Dieppois et al

Educate about possible drowsiness and fatigue

Studies have shown that these blockers can reduce BBB leakage and improve cognitive outcomes in animal models of I/R injury, suggesting their potential as a therapeutic strategy to prevent BBB dysfunction and cognitive decline (Xiong et al., 2020

This temporal lag in establishing fluid and electrolyte homeostasis, if timed correctly, may be implemented to induce diuresis before the protective homeostatic mechanisms fully manifest to halt water loss