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Next, 18 l of the soluble polar metabolite supernatant was transferred to sample vials for analysis by LCMS as previously described 4,28

When IgG4-RD involves the central nervous system or surrounding areas, it may cause: Persistent headaches Eye pain or swelling Facial numbness Neurological symptoms like vision or hearing changes Chronic sinus problems These symptoms may resemble migraines, tension-type headaches, or sinus infections, which is why understanding the link between IgG4-RD and chronic headaches is essential

189 Among these HNP1, 2 and 4, especially HNP1 has been reported to be highly expressed at wound center as compared to wound edges, suggesting massive infiltration of neutrophils at wound center as observed during normal circumstances