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Exposing murine pancreatic -cells to pro-inflammatory cytokines IL-6 and IL-1 led to changes in the cell metallome, especially a decrease in Zn and Ca content and an increase in Fe content, together with changes in the cellular distribution of these metals

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Finally, phosphorylation of S377 on AMPK2 associated with glucose uptake in insulin-stimulated and/or exercised skeletal muscle from individuals with differing muscle insulin sensitivity, and was necessary for proliferation of MEF cells during glucose deprivation, suggesting a regulatory role in glucose metabolism [35]