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4 Genetic influence on pharmacodynamics and pharmacokinetics The therapeutic Pharmacogenetics investigates how genetic variability influences individual responses to conventional pharmacological treatments, given that genetics can interfere with both the efficacy and toxicity of a drug

The models were conditioned on the matching variables and adjusted for education, country of birth and the Charlson comorbidity index

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease

Surprisingly, glutathione depletion in mice extended lifespan, challenging assumptions