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Description

Curcumin stops platelets from sticking together , which can help prevent blood clots

Additionally, free heme can generate the reactive nitrogen species peroxynitrite that can further oxidative stress 61

In various embodiments, the method comprises providing the epoxide by reacting an compound of the formula (XVII-A) wherein LG is a leaving group: In various embodiments, the compound of formula (XVII-A) is prepared from L-aspartic acid