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Description

p53 transactivation domain mediates binding and phase separation with poly-PR/GR

- Creatine (Cr) and Phosphocreatine (PCr): representing the brain's energy reserves

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Although experimental structural information on DIDO SPOC is lacking, AlphaFold2 structure prediction 26,27 shows that the conserved residues cluster in patches on the domain surface similar to PHF3 SPOC (Fig