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We first established a computational protocol to evaluate the stability and binding affinity of all possible single point mutants with pAcF incorporated

Similarly, according to the DrugBank [36, 37] database ( accessed July 7, 2020), the target of fluconazole is the yeast CYP51, and interactions with human CYP3A4, 3A5, 2C9, and 2C19 are listed

Guo X, Zhu Y, Hong X, Zhang M, Qiu X, Wang Z, et al

The once widely accepted primary role for -amyloid in sporadic AD (known as the amyloid cascade hypothesis) is currently criticised as not being the sole cause of AD, but nevertheless, amyloid accumulation is clearly a part of AD pathology and evokes multifaceted glial responses