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34 In a similarly sized double-blind, placebo-controlled study of intravenous ketamine (0.2 mg/kg) for treatment of migraine in the emergency department setting, however, ketamine was not superior to placebo for acute pain relief and caused adverse effects of generalized discomfort at 30 minutes and fatigue at 60 minutes, although no serious adverse events occurred

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Mol Cell (2015) 60(1):720.10.1016/j.molcel.2015.08.016 25 RichterBSliterDAHerhausLStolzAWangCBeliPet alPhosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria

Start with the label directions, introduce gradually, and track appetite and stool quality