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Description

Collagen I accumulation can inhibit load-induced growth in mice 33 , perhaps due to the inability of critical transmembrane mechanosensors in muscle fibers (dystrophin, integrins) to adhere to laminin in the basement membrane 49,50

(2010) 12:R17

During the study, female mice were given metformin alone at 500 mg per kg, melatonin at 1mg per kg, or a combination of melatonin at 2mg per kg with testosterone