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Description

GSNO treatment increases PHGDH S-nitrosation and inhibits its enzymatic activity

Safety and efficacy data in pregnant populations remain under active investigation

10.1002/ardp.201000181 32 BrambillaE.CagettiM

These patterns are consistently observed in diverse mouse models, including wild type and transgenic mice across various strains, as highlighted in a review by Wood and Zuo (27)