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Anagen/catagen classification was performed according to previously established morphological criteria reported in prior human hair follicle organ culture studies [14]: in the fully mature anagen VI stage, terminal hair follicles are characterized by a well-defined, onion-like hair bulb and a slim, elongated dermal papilla

Glutathione synthesis is induced by oxidative stress, which stabilizes nuclear factor erythroid 2related factor 2 (NRF2) to induce the transcription of both GCLC and GCLM and a battery of antioxidant enzymes that detoxify reactive oxygen species (ROS) (Harris and DeNicola, 2020)

10.1016/j.ejphar.2013.08.045 92 PeiB.YangM.QiX.ShenX.ChenX.ZhangF

GLP-1 agonists, such as semaglutide or tirzepatide, act on the GLP-1 receptor to suppress appetite and to regulate glycemia