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Cells within the mononuclear phagocyte system (MPS) remove senescent blood cells via phagocytosis and digestion

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FIGURE 11 AC5 and AC6 inhibitors for the treatment of heart failure As AC5 deletion appears to be protective in heart failure, there has been much research into isoform-selective AC5 inhibitors, which may be advantageous over -blockers (Pierre et al., 2009)