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10.1111/ced.12664 124 LuY.YinL.YangW.WuZ.NiuJ

In those studies, ROS emerged as the main culprit that induced internal apoptosis [61]

They are not approved as food supplements, medicines, or therapeutic products

In addition, IGF-1 LR3 may promote fat breakdown by activating the MAPK pathway, leading to increased levels of free fatty acids and further exacerbating insulin resistance, forming a vicious cycle