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With Convention Automatic Presumptive Linkage Coding Clinic has clarified that the with convention in ICD-10-CM Guideline I.A.15 establishes a presumptive causal relationship based on the Alphabetic Index structure alone no explicit documentation of causation is required from the provider

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Discussion Here we show that zonula occludens toxin (Zot, or zonulin), a potent regulator for intestinal TJ competency and intestinal barrier function, is controlling the onset of murine and human arthritis