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SKU: 10658460668
Price: 25.93 USD
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Description

Unlike other treatments such as semaglutide and tirzepatide, which act on only one or two receptors, Retatrutide is a triple receptor agonist

doi: 10.3390/nano9101365

This effect is blocked by glutamatergic antagonist CNQX [cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione)] and AP5 (2-amino-5-phosphopentanoic acid), suggesting that interneuron-astrocyte-mediated potentiated inhibition of pyramidal neurons depends on astrocyte-mediated glutamate release (Kang et al., 1998)

At least 10 cells (membrane sheets) per experiment ( n = 3) were imaged, and ten ROIs (10 10 m each) were selected from different regions of each image for dot density quantification after deconvolution (DeconvolutionLab2 in ImageJ)