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SEO1 was induced under conditions where no methionine was added, whereas in the presence of methionine it was repressed

Pathogenesis of Tissue Deposition of Urate Crystals Into Tophi Besides tissue supersaturation with urate and the effects of decreased temperature and decreased tissue pH to promote decreased urate solubility, other factors promote the transformation of soluble urate into urate crystals deposited in tophi ( Figure 1 - 6 )

For instance, ABA biosynthesis genes such as NCED and ABA-responsive transcription factors show heightened expression under Mg deficiency, intensifying stress responses, whereas Mg sufficiency modulates ABA signaling to optimize water-use efficiency ( 7.3 Sensing low magnesium in plants Plants have developed sophisticated mechanisms to detect and respond to Mg deficiency, ensuring their survival under changing nutrient conditions