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Standard clinical dosing starts at 2.5 mg once weekly, increasing to 5 mg after 4 weeks, with further 2.5 mg increments every 4 weeks as needed

Insulin syringes are used to measure small and accurate units

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For example, as shown in Table 59, if CMS grants a severe supply chain disruption rebate reduction request for a Part B biosimilar biological product for 4 calendar quarters, CMS will apply the rebate reduction beginning with the first applicable calendar quarter for which the reduction request was granted, regardless of whether the biosimilar biological product meets the definition of a Part B rebatable drug or is subject to a rebate amount in that calendar quarter