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The tail suspension test indicates that withdrawal from NEP increases the immobility time in mice, suggesting that drug withdrawal can trigger depression-like symptoms 46,47

In vivo sensitisation of tumours by rhGH To extend and validate this study in vivo , we decided to use the anticancer drug daunorubicin, as TNF- , one of the main cytokines involved in sepsis (reviewed in Dinarello, 2000), may induce devastating effects after in vivo injection