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NB has shown remarkable benefit in patients with binge-eating disorder (BED) and concomitant alcohol abuse, but this result needs further evaluation (62)

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These include vitamin B12 deficiency and malabsorption that is caused by the following medical conditions, according to the NIH [1]: Pernicious anemia Tropical sprue Pancreatic insufficiency Surgery in the gastrointestinal tract Certain medications Deficiency in the diet Side effects of B-12 injections Also, according to the NIH, vitamin B-12 injections have some potential side effects, including [1]: Diarrhea Itching Swelling Risk of allergic reaction and anaphylaxis Can Vitamins Aid in Weight Loss

By inhibiting NNMT, 5-Amino-1MQ increases intracellular NAD levels and enhances metabolic activity: NNMT Inhibition: Reduces methylation-driven energy conservation pathways, shifting the body toward increased energy expenditure