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In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis

IV drips with N-acetyl cysteine have been used to detoxify the body of too much acetaminophen in medical settings for years

55,56,57 Recently, the first gene therapy based on clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 technology has been approved for marketing, 58 resulting in revolutionary changes in NADs development

The glioma microenvironment is exceptionally complex and exhibits significant heterogeneity in treatment response