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In conclusion, OA pathogenesis is propelled by a metabolically dysregulated milieu, where obesity, oxidative stress, gut dysbiosis, and broader metabolic syndrome converge to create a self-perpetuating cycle of inflammation and tissue damage (Figure 1)

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However, with Dr.Esthers ODF Technology, it is absorbed directly into systemic circulation through oral mucosa, rather than pass though the intestinal absorptive mechanisms, portal cirulation or liver

You can walk out of the clinic and resume your normal activities immediately after the treatment