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Nat Rev Cardiol 21 , 682700 (2024)

3.2 Microbial sources functional factors Compared with the animal-derived functional factors reviewed above, which act largely through protein-based bioactive compounds that modulate anabolic signaling and reduce muscle catabolism, microbial-derived functional factors share some immune and antioxidant properties but are distinguished by a primary focus on enhancing endurance rather than strength, acting through mechanisms that are detailed in this subsection