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Glutamine, a nonessential amino acid, is the most common free amino acid found in body fluids and skeletal muscles and has a pivotal role in regulating cell proliferation and growth [30] as well as stimulating incretin hormones, particularly GLP-1 secretion [15]

Studies have consistently shown elevated levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-), and other inflammatory cytokines directly inhibit Leydig cell function and reduce LH sensitivity

In CRC, the reactivation or remodeling of mitochondrial metabolic pathways, particularly oxidative phosphorylation (OXPHOS) and fatty acid oxidation (FAO), is closely associated with key oncogenic processes such as the evasion of apoptosis, the maintenance of cancer stem cell properties, and the regulation of redox homeostasis [5,6,7,8]

putrefaciens and the ambient spoilage by Vibrionaceae which is dominated by H 2 S and TMA, the spoilage caused by Pseudomonas spp