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Cagrilintide Synonyms / Designations: Cagrilintide, AM833, Long-acting amylin analogue, Dual amylin receptor agonist CAS Number: 1415456-99-3 Molecular Formula: C194H312N54O59S2 Molecular Weight: 4409.01 g/mol Peptide Classification: Synthetic long-acting amylin analogue Purity: 99 % (HPLC, typical) Appearance: White to off-white lyophilised powder Pack Size: Research pack size (varies) Storage: Desiccated, protected from light, stored at 20 C Solubility: Soluble in sterile water and buffered aqueous solutions Description & Mechanism Cagrilintide is a synthetic long-acting analogue of the endogenous peptide hormone amylin, developed for experimental investigation of amylin receptor signalling and metabolic regulation

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Most, although probably not all glucose oxidation in astrocytes proceeds via glutamate formation, astrocytes account for 20% of total glucose oxidation rate, or 0.14 mol/g per min (in the rat), and one half of glutamate formation (0.07 mol/g per min) occurs via pyruvate carboxylation (with the other one half mediated by PDH)

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