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Adv Pharmacol 38:247269

Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, et al

However, blood levels of NO break down quickly

In addition to forming cancer cells, ROS overproduction contributes to cell migration by degrading the extracellular matrix, disrupting cell-to-cell contact, remodeling the cytoskeleton, regulating gene expression, and forming invadopodia [82]