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Description

Up to 40-50% of the population in the US is deficient in vitamin B12

The subsequent transport of liberated cobalamin from the lysosome to the cytosol relies on the coordinated action of two integral membrane proteins, lipocalin-1-interacting membrane receptor domain-containing 1 (LMBD1) and adenosine triphosphate (ATP)-binding cassette subfamily D member 4 (ABCD4)