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Pushie et al., 2007

Bladder Instillations Bladder instillations are administered by the patients themselves, using a very small, pre-lubricated, pediatric catheter, usually twice per day for two weeks

While it is unclear whether epigenomic changes are an essential element of ageing and how these changes occur during ageing remain elusive, many attempts are on the way to depict the full landscape of acute and chronic changes in the epigenetic modification during stem cell ageing