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J Exp Bot 67:16631676 Mou Z, Fan W, Dong X (2003) Inducers of plant systemic acquired resistance regulate NPR1 function through redox changes

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GHK-Cu is a tripeptide composed of three amino acids with a high affinity for copper ions

It remains to be investigated whether changing the amino acid sequence of ROXY9 into the sequence of class I GRXs at the discussed positions will be sufficient for a gain of function with respect to oxidoreductase activity, or whether other structural perturbations in the protein are responsible for its dysfunctionalized oxidoreductase activity