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How Injection Site Selection Affects Treatment Tolerance Some patients experience different levels of injection-site discomfort, bruising, or localized reactions depending on the anatomical region chosen

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We proposed at 428.401 the use of an initial Preliminary Rebate Report and a subsequent Rebate Report, with an ( opportunity for manufacturers to identify certain mathematical errors (see 428.403 and discussed in further detail later in this section) and two regular reconciliations of the rebate amount to account for updates to claims and payment data at 12 months and 36 months after the Rebate Report is issued as set forth in 428.401(d)