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This, in turn, disrupted the normal cellular activity and triggered apoptosis, which ultimately led to a loss of ovarian reserve (Liu et al

However, therapeutic valproate serum concentration for most patients with absence seizures is considered to range from 50 to 100 mcg/mL

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However, blockade of inward rectifying K-channels (K ir ) depolarizes the neuron, prolongs depolarization, and leads to either epileptiform activity or cellular death (see Figure 3)