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This PHB2- CEBPB -NOX1 cascade activates the ERK/MAPK pathway, promoting tumorigenesis and metastasis [32]

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

Kryczka and Boncela, 2018

To further test whether this effect is mediated by periodontitis-induced N1-polarized BM neutrophils, BM neutrophils from control and ligatured WT donor mice were adoptively transferred into db/db recipient mice (Con-Neus and Lig-Neus) (Fig S8a)