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385 Mito-TEMPO (MT), another mitochondrial superoxide scavenger, also prevents muscle atrophy via alleviating mitochondrial dysfunction, oxidative stress and inflammatory

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In recent years, ferroptosis has emerged as a promising target for countering highly aggressive malignancies, and is an iron-dependent form of regulated cell death associated with accumulation of reactive oxygen species (ROS) and increased lipid peroxidation 7

It is standard practice in Bayesian trial design methodology 55 to use a community of priors, also known as adversarial priors, whereby an enthusiastic prior is used for futility monitoring while a more skeptical prior is used for the final analysis