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The Key Structural Difference: Glycine vs Alanine Both peptides are three amino acids long

Similarly, in human mast cells FAHF-2 (20 g/mL) treatment inhibited degranulation [40]

However, the high sequence identity (53%) and the same active site shared between human fumarase and Mtb fumarase pose a challenge in developing anti-tuberculosis drugs targeting this enzyme [287]