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Additionally, TGF- and IL-10 dampen autoimmune responses (Wise et al., 2000)

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42 , W187W191 (2014)

Furthermore, the competitive, independent, or sequential binding of Pin1 and Lck to PKC may differ among T cell subtypes and thereby explain the differential recruitment of PKC to the IS of Th/Tc vs its recruitment to the opposite cell pole in Treg