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Spray administration: Administer a measured amount of the TB-500 nasal spray by gently pressing the applicator, releasing the spray into the subject's nostril

The significantly reduced CAT activity in the G1 groups serum suggests overwhelming oxidative stress as a result of a diabetic condition, thus, indicating increased production of oxygen-free radicals, which could be linked with persistent hyperglycemia, otherwise known as high blood glucose (Takemoto et al

Pereira da Silva L, Miguel Neves B, Moura L, Cruz MT, Carvalho E (2014) Neurotensin decreases the proinflammatory status of human skin fibroblasts and increases epidermal growth factor expression

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