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doi: 10.1038/81834

Quercetin also inhibits protein disulfide isomerase (PDI) enzyme involved in platelet-mediated thrombin formation, thus could ameliorate coagulation abnormalities in PASC 625

In addition, ceramides act as active second messengers, regulate the proliferation and differentiation of keratinocytes, enhance the production of pro-inflammatory cytokines, and modulate the immune response

Inhibition of CB1, CB2 and TRPV-2 receptors has also been shown to reverse some of the anti-cancer effects of CBD, however the pathways involved are not yet fully understood [3, 11]