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Moreover, elasticity, hydration, flux, wrinkle and glamour of skin were also enhanced when pycnogenol was administrated on both human and animal model [35,36]

167 Evasion of apoptosis brought about by H 2 S has been attributed mostly to CSE-generated H 2 S mediating the per-sulphidation of key proteins in different signalling pathways: nuclear factor-B (NF-B) in hepatoma cells, 168 the Keap1-transcriptional regulator of NRF2, 169 and the extracellular-signal-regulated kinase (ERK)-activating protein kinase 1

doi: 10.3390/ijms18020278 [DOI] [PMC free article] [PubMed] [Google Scholar] 180

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