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370 In HCC, CDKN2A promotes tumor cell proliferation and migration capabilities as well as attenuating cuproptosis

Considering its low absorption and rapid metabolism by oral, some modification is required to optimize its bioavailability, the spherical nano-curcumin micelles have been tested in the clinical trial, the primary result is promising, and further research is warranted (135)

The IL-22-responsive transcriptional module is significantly enriched in both mouse colitis models and human UC, with elevated levels of neutrophil-active chemokines such as Cxcl1 , Cxcl2 , Cxcl3 , and Cxcl5 [94]

Functional genomic studies of the intestinal response to a foodborne enteropathogen in a humanized gnotobiotic mouse model