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In 1993, additional positive surface markers [such as CD10, CD44, CD29, VLA-1, VLA-5, and vascular cell adhesion molecule 1 (VCAM-1)] and negative markers (such as CD14, CD34, CD45, LFA-1a, LFA-1b, LFA-3, VLA-2, VLA-4, VLA-6, and Stro-1) associated with MSCs were further identified