Research Projects Identification of the cellular source of new hepatocytes after regeneration and the source of liver cancers during chronic injury Identify and functionally assess somatic mutations in liver disease Understanding the influence of regenerative capacity on cancer Identification of the cellular source of new hepatocytes after regeneration and the source of liver cancers during chronic injury Identify and functionally assess somatic mutations in liver disease Understanding the influence of regenerative capacity on cancer Lab News Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help mutated cells Cancer Biology, Regenerative Medicine Select Publications Guo, J.*, Liang, R.*, Chung, A.*, Li, Z.*, Li, B., Chen, E., Li, L., Wang, J., Hsieh, M.H., Fang, I.X., Kroger, B., Wang, Y., Zhu, M., Ren, X., Mannino, G., Jia, Y., Wei, Y., Moore, S., Siegwart, D.J., Chung, S.S., Wang, Z., Sharma, T., Komjeti, S., Han, Y., Gopal, P., Xiao, G., Wang, T., and H

Wekerle, H., Linington, C., Lassmann, H
Although CntA/B may be responsible for some TMA formation by -proteobacteria intimately associated with the intestinal epithelium using oxygen that diffuses into the luminal content, because of its oxygen requirement, it is unlikely to be the primary physiologic source of l-carnitineTMA activity in the mostly anoxic luminal intestinal environment
Acta 1826 , 4452 (2012)