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& Coffey, B

While some users report enhanced local effects, the evidence for superiority over subcutaneous administration remains unclear, and complications including nerve irritation present greater concern

[PMC free article: PMC486958] [PubMed: 5031636] 18

Patients are advised of the significance of standardized, GMP-certified product formulations, proper dosing and tailor it to timing relative to chemotherapy or endocrine therapy