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X-ray crystallography and NMR analysis revealed that HSP70 bound to the amino (N)-terminal flexible region and glutathione S-transferase domain of AIMP2-DX2 through its substrate-binding domain

Nature Cell Biology, 12(9), 814822

Substituents can include any substituents described herein, for example, a halogen, a hydroxyl, a carbonyl (such as a carboxyl, an alkoxycarbonyl, a formyl, or an acyl), a thiocarbonyl (such as a thioester, a thioacetate, or a thioformate), an alkoxyl, a phosphoryl, a phosphate, a phosphonate, a phosphinate, an amino, an amido, an amidine, an imine, a cyano, a nitro, an azido, a sulfhydryl, an alkylthio, a sulfate, a sulfonate, a sulfamoyl, a sulfonamido, a sulfonyl, a heterocyclyl, an aralkyl, or an aromatic or heteroaromatic mo references to chemical moieties herein are understood to include substituted variants

This method is frequently combined with other hair restoration techniques as a treatment for hair loss