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10.1038/nrneph.2017.107 14 Briones-HerreraA.Avila-RojasS

Fetal reversion enables villus-derived cells to regenerate tissue without exogenous oncogenic mutations To determine whether the fetal reversion and subsequent conversion to CBCs observed in Alpi+ enterocytes in vitro could also occur under more physiological conditions, we performed primary collagen culture of villus tissues containing tdTomato-labeled Alpi+ cells, followed by in vitro organoid expansion and subsequent transplantation experiments using a DSS-induced colitis model 23,24

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Before your first treatment, your provider will walk you through the process in detail and review your medical history