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Description

Synaptic vesicles in nerve terminals of glutamatergic neurons are loaded with glutamate

The reasoning strongly suggests no clinically significant pharmacokinetic interaction, but pharmacodynamic nuances related to GH-axis stimulation remain incompletely characterized

Side effects, safety & contraindications In trials the most commonly reported side effects were gastrointestinal, including nausea, vomiting, constipation, and decreased appetite, generally described as dose-related and more frequent during dose escalation

doi: 10.3389/fphar.2025.1524654 Received 08 November 2024 Accepted 29 April 2025 Published 14 May 2025 Volume 16 - 2025 Edited by Hua Li, Air Force Medical University, China Reviewed by Xie-an Yu, Shenzhen Institute For Drug Control, China Bing Yu, Second Military Medical University, China Updates Copyright 2025 Ma, Chu, Quan, Li, Zhou, Han, Li, Pan, Wang, Yan, Shu and Qiao