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We showed that the GCLC mRNA expression level was downregulated by ACTL6A KD and was upregulated when ACTL6A was overexpressed, but the GCLM expression was not changed (Supplementary Fig 5a, b)

Les essais cliniques ont montr des augmentations mesurables des niveaux de GSH tissulaire ds 1 mois de supplmentation, avec des amliorations continues pendant 6 mois