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This means that in the same study, one can evaluate lung inflammation (BALF analysis, gene and protein expression analysis, histopathology), emphysematous changes (histopathology), lung function, and lung carcinogenesis (histopathology) together with carcinogen exposure (biomarkers of exposure, metabolic responses to carcinogen exposure [gene and protein expression]) and the response to DNA damage based on gene expression data

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Front Physiol 4:242 Noerager BD, Xu X, Davis VA, Jones CW, Okafor S, Whitehead A et al (2015) A potential role for acrolein in neutrophil-mediated chronic inflammation

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