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Given the widespread use of doxycycline, in both short and prolonged regimens, it is important to recognise this reversible or partially reversible side effect in order to discontinue therapy

TrkB serves as a receptor for the brain-derived neurotrophic factor (BDNF), which is involved in the transcription, translation and trafficking of proteins at various stages of neuronal development and synaptic plasticity, which, in turn, is associated with learning and memory development