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Pleiotropy and heterogeneity were absent (Tables S5)

Vojdani A, Campbell AW, Anyanwu E, Kashanian A, Bock K, Vojdani E

This documentation takes about 60 seconds per entry

Thus, the cysteine takes the second place in its conservativity, because its score is the mean score for all cysteine residues regardless of their involvement to the formation of disulfide bridges